I think a Futurama
movie (be it theatrical or DTV) would absolutely turn a profit. Think of all the work's that been done already: character designs and casting processes and background animations, etc.
I doubt the cast members would demand any massive paydays, and I've no doubt that MG, DXC and the screenwriters would be able to come up with something damn good.
Let's not forget about a little TV show called Star Trek
; a highly underappreciated sci-fi series that was canceled before its time, earned itself a fiercely loyal fanbase through syndication, and then launched a series of ten movies, a half-dozen TV spinoffs and an incalculable number of toys, games, etc., etc.
And that was freakin' STAR TREK
What pleases me most is that the two honchos (Groening and Cohen) actively want
to pursue a Futurama
movie! If they stick to their guns, I suspect we actually could see a movie some day...and with those guys at the helm - it's highly unlikely that the movie turns out to be a turkey.
Ah well, we can hope.