My fave is from March, with all the cloning tubes and baby Planet Express staff coming out. Professor Farnsworth's expression is priceless!
And I love how the rest of the adult Planet Express gang are looking at him in shock, suprise, and disbelief. And I think it's a really nice image, well layed out, and it's in an almost graphic type style with the cloning tubes and typography. Although it's not tecnically the same, I think the inspiration for this picture came from 'Teenage Mutant Leela's Hurdles'
Also, I don't see the need for spoilers in this thread, because if you haven't got it, there's no need be in here.