Now now coldangel, let him write the sequel first - *then* destroy him.
On a more serious note, I kinda got the impression from the end that Sam, Leela, and Fry might (eventually) end up in some kind of three-way relationship - it is the future, after all. (Admittedly, this is more circumstantial than anything else, but I did somewhat get that sense.) And as Fry apparently hasn't entirely given up on Leela...unlikely? No more so than heads in jars!
Archonix: Phi is, I'd say, not entirely Fry anymore. That is, she's grown and developed in ways that Fry could not. (Not that I want tell you your business, so to speak.
) She's still basically the person she was as a man, but now she's a woman. And one thing certainly hasn't changed, which would provide some great tension for a sequel...good luck!