I know it’s been mentioned once before, on page 3 of the thread, but my top favorite Futurama exclamation, for sheer unexpectedness, is...
Kif: “Oh, monkey trumpets!”
That one made me laugh loud enough to startle my dog. Hee!
Also mentioned before, but hilarious just for the sheer level of exasperation, is Hermes’ “That's a plus sign, you pointy-haired loony! Quit thinkin’ you’re a robot!!”
But I believe these are new to the thread:
Leela, in AOI2: “Oh, for the love of Benji!”
Leela, some other episode: “For Heaven’s Gate, Professor!”
(In fact, most of Leela’s slightly twisted exclamations are great... )
Fry: “You gotta help me, Bender. How can I prove I’m human?”
Bender: “You could drop dead. That’d show ‘em.”
Fry: “I don’t waannnna!”
Fry, to Morgan Proctor: “What are you doing now?! Stop doing things!
Amy, at her first sight of sunken Atlanta: “(something Chinese) dude!”
Bender, snowboarding: “Lick my frozen metal ass!”
Fry, watching Bender on camera: “Hey! It’s that guy you are!”
Munda: “Leela, forgive us! Especially your father, who’s the one who blabbed, thank you very much Morris!”