Some things that struck me as odd in this episode have answers suggested by later episodes; others, I just wanna sees what youse guys thinks...
1) Why does Leela go to all the trouble she does, to stop the gang from getting rid of Fry's worms? I mean, she's experiencing everything her microbot does through her netsuit; travelling down Fry's mucous-coated throat, through his "upset" stomach and part of his colon--without benefit of a ship or suit. Ew. She could've simply put her real axe through the lines connecting everyone's netsuits. She would have risked winding up broke, fired, or even arrested--but she wouldn't be as familiar with Fry's pooptubes as she is now. Ewwwww.
Possible explanation: Leela's not kidding when she talks about her "mental illness" in "Leela's Homeworld." In "Anthology I," the What-If Machine suggests she is capable of murdering everyone; in "Anthology II," she kills Amy and disfigures everyone else--in the "nicest dream." She's angry to see everyone alive and okay when she wakes up. Her life-experiences have left her with a lot of frustration. Why pass up a chance to legally attack everyone with an axe?
2) Speaking of "Anthology I"--everyone in the room was watching Leela slaughter them like pigs on the WIM. How do you suppose they reacted? I'll bet the Professor put a grate over his man-eating anteater pit...
3) Some people blame Leela for the disasterous end of her and Fry's courtship in "Lost," because of her "...what you've become" line. But the worms didn't actually change Fry, they just helped him reach his full potential in a mutually-beneficial symbiotic relationship. Other people would kill for those worms. So:
a) Who's the real screw-up here?
b) Would YOU have gotten rid of them?
c) Where did they go? Is Violet stronger, faster, better now? Is Amy stronger and more flexible than Gumbercules? Nibbler?
4) Ew. What happened to the microbots? Is there a "dead" Futurama cast stuck in the lining of Fry's intestines? Ewwwwww.
"Hooray!! It's just like Mardi Gras!!"